Autism spectrum disorders: is mesenchymal stem cell personalized therapy the future?
Siniscalco D, et al. Show all Journal
J Biomed Biotechnol. 2012;2012:480289.
Abstract
Autism and autism spectrum disorders (ASDs) are heterogeneous neurodevelopmental disorders. They are enigmatic conditions that have their origins in the interaction of genes and environmental factors. ASDs are characterized by dysfunctions in social interaction and communication skills, in addition to repetitive and stereotypic verbal and nonverbal behaviours. Immune dysfunction has been confirmed with autistic children. There are no defined mechanisms of pathogenesis or curative therapy presently available. Indeed, ASDs are still untreatable. Available treatments for autism can be divided into behavioural, nutritional, and medical approaches, although no defined standard approach exists. Nowadays, stem cell therapy represents the great promise for the future of molecular medicine. Among the stem cell population, mesenchymal stem cells (MSCs) show probably best potential good results in medical research. Due to the particular immune and neural dysregulation observed in ASDs, mesenchymal stem cell transplantation could offer a unique tool to provide better resolution for this disease.
Source: Division of Pharmacology “L. Donatelli”, Department of Experimental Medicine, Second University of Naples, Via S. Maria di Costantinopoli, 16-80138 Napoli, Italy.
supported by
AUTISM CLINIC ONLINE
CHILDREN GRoW UP CLINIC
Yudhasmara Foundation http://childrengrowup.wordpress.com
- CHILDREN GRoW UP CLINIC I, Jl Taman Bendungan Asahan 5 Bendungan Hlir Jakarta Pusat phone (021) 5703646 – (021) 44466102
- CHILDREN GRoW UP CLINIC II, Menteng Square Jl Matraman 30 Jakarta Pusat 10430 phone 44466103 – 977730777
- email :
WORKING TOGETHER SUPPORT TO THE HEALTH OF ALL CHILDREN BY CLINICAL, RESEARCH AND EDUCATIONS. Advancing of the future pediatric and future parenting to optimalized physical, mental and social health and well being for fetal, newborn, infant, children, adolescents and young adult
LAYANAN KLINIK KHUSUS “CHILDREN GRoW UP CLINIC”
PROFESIONAL MEDIS “CHILDREN GRoW UP CLINIC”
|
Clinical – Editor in Chief :
Dr WIDODO JUDARWANTO SpA, pediatrician
- email :
- curriculum vitae
- For Daily Newsletter join with this Twitter https://twitter.com/WidoJudarwanto
Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. You should carefully read all product packaging. If you have or suspect you have a medical problem, promptly contact your professional healthcare provider
Copyright © 2012, CHILDREN GRoW UP CLINIC Information Education Network. All rights reserved
